NO.

Time

Article

Journal

Author

1

2018

Sequential allogeneic and autologous CAR-T cell therapy to treat an immune compromised leukemic patient.

Blood Advances 2, 1691-1695

Jian-Ping Zhang, Rui Zhang, Shih-Ting Tsao, Yu-Chen Liu, Xiaochuan Chen, Dao-Pei Lu, Paul Castillo, Lung-Ji Chang

2

2018

Phase I/II Trial of Multi-Target Chimeric Antigen Receptor Modified T Cells (4SCAR2.0) Against Relapsed or Refractory Lymphomas

Blood (2018) 132 (Supplement 1): 225

Lung-Ji Chang, Yuhua Li, Sanfang Tu, Xun Lai, Rui Huang, Shih-Ting Tsao, Yu-Chen Liu, Rui Zhang, Lan Deng, Xuan Zhou, Hongyu Zhang, Wenli Zhang, Yuchen Li

3

2018

CD70 as a target for chimeric antigen receptor T cells in head and neck squamous cell carcinoma

Oral Oncology 78 (2018) 145–150

Yuk Pheel Park，Linchun Jin，Katie B. Bennett，Dunrui Wang，Kristianna M. Fredenburg，Jennifer E. Tseng，Lung‐Ji Chang，Jianping Huang，Edward K.L. Chan

4

2019

Adoptive immunotherapy for B-cell malignancies using CD19-targeted chimeric antigen receptor T-cells: A systematic review of efficacy and safety.

Current Medicinal Chemistry, 2019

Jennifer E. Tsengf , Lung‐Ji Changg,⁎ , Jianping Huangb,⁎ , Edward K.L. Chana,⁎

5

2019

Shortening the ex vivo culture of CD19-specific CAR T-cells retains potent efficacy against acute
lymphoblastic leukemia without CAR T-cell-related encephalopathy syndrome or severe cytokine release syndrome.

Am J Hematol. 2019

Sanfang Tu, Rui Huang, Zhenling Guo, Lan Deng, Chaoyang Song, Xuan Zhou, Chunyan Yue, Lenghe Zhang, Yanjie He, Jilong Yang, Zhao Liang, Jingwen Du, Peihua Cao, Yushen Li, Lung-Ji Chang, Yuhua Li

6

2019

Chimeric antigen receptors T cells for treatment of 48 relapsed or refractory acute lymphoblastic leukemia children: long term follow-up outcome.

Zhonghua Xue Ye Xue Za Zhi
. 2019 Apr 14;40(4):270-275

Y X Zuo, Y P Jia, J Wu, J B Wang, A D Lu, L J Dong, L J Chang, L P Zhang

7

2019

Functional Improvement of Chimeric Antigen Receptor Through Intrinsic Interleukin-15Rα Signaling.

Curr Gene Ther. 2019;19(1):40-53

Sushmita Nair, Jing-Bo Wang, Shih-Ting Tsao, Yuchen Liu, Wei Zhu, William B Slayton, Jan S Moreb, Lujia Dong, Lung-Ji Chang

8

2019

CD19 and CD70 Dual-Target Chimeric Antigen Receptor T-Cell Therapy for the Treatment of Relapsed and Refractory Primary Central Nervous System Diffuse Large B-Cell Lymphoma.

Front Oncol. 2019 Dec 4;9:1350

Sanfang Tu, Xuan Zhou, Zhenling Guo, Rui Huang, Chunyan Yue, Yanjie He, Meifang Li, Yiran Chen, YuChen Liu, Lung-Ji Chang, Yuhua Li

9

2019

CD56-chimeric antigen receptor T-cell therapy for refractory/recurrent rhabdomyosarcoma: A 3.5-year follow-up case report

Medicine (Baltimore). 2019 Oct;98(43):e17572

Chiyi Jiang, Wen Zhao, Maoquan Qin, Mei Jin, Lungji Chang, Xiaoli Ma

10

2019

Hemophilia Gene Therapy: New Development from Bench to Bed Side

Current Gene Therapy. 2019; 19: 264-273.

Xiao-Lu Guo, Tsai-Hua Chung, Yue Qin, Jie Zheng, Huyong Zheng, Liyuan Sheng, Tung Wynn, Lung-Ji Chang

11

2020

Successful Anti-CLL1 CAR T-Cell Therapy in Secondary Acute Myeloid Leukemia

Front Oncol. 2020 May 27;10:685

Hui Zhang, Wen-Ting Gan, Wen-Ge Hao, Peng-Fei Wang, Zhuo-Yan Li, Lung-Ji Chang

12

2020

GD2-specific chimeric antigen receptor-modified T cells targeting retinoblastoma – assessing tumor and T cell interaction

Transl Oncol. 2021 Feb; 14(2): 100971

Jatuporn Sujjitjoon, Elias Sayour, Shih-Ting Tsao, Mongkol Uiprasertkul, Kleebsabai Sanpakit, Jassada Buaboonnam, Pa-thai Yenchitsomanus, La-ongsri Atchaneeyasakul, and Lung-Ji Chang

13

2020

GD2 chimeric antigen receptor modified T cells in synergy with sub-toxic level of doxorubicin targeting osteosarcomas

Am J Cancer Res 2020;10(2):674-687

Monrat Chulanetra, Atthapan Morchang, Elias Sayour, Lamis Eldjerou, Rowan Milner, Joanne Lagmay, Matt Cascio, Brian Stover, William Slayton, Wanpen Chaicumpa, Pa-Thai Yenchitsomanus, Lung-Ji Chang

14

2020

4SCAR-GD2-modified T-cell therapy in neuroblastoma with MYCN amplification: A case report with over 4-year follow-up data

Pediatr Invest 2020 Mar; 4 (1): 55-58

Xiao Xu, Wen Zhao, Zhixia Yue, Maoquan Qin, Mei Jin, Lung-Ji Chang, Xiaoli Ma

15

2021

4SCAR2.0: a multi-CAR-T therapy regimen for the
treatment of relapsed/refractory B cell lymphomas

Blood Cancer J. 2021 Mar 17;11(3):59

Cheng Jiao, Eugene Zvonkov, Xun Lai, Rui Zhang, Yuchen Liu, Yue Qin, Valery Savchenko, Nelly Gabeeva, Tsai-Hua Chung, Liyuan Sheng, Lung-Ji Chang

16

2021

4SCAR2.0 Treating Refractory B Cell Lymphomas: An Advanced Technology Saves More Lives

iMedPub Journals 7:3

Jiao C, Sheng L, Chang L-J

17

2021

Chimeric antigen receptor T cells targeting CD7 in a child with high-risk T-cell acute lymphoblastic leukemia

Int Immunopharmacol. 2021 Jul;96:107731

Lichun Xie, Lian Ma, Sixi Liu, LungJi Chang, Feiqiu Wen

18

2021

A Glimpse into the Diverse Cellular Immunity against SARS-CoV-2

Vaccines (Basel). 2021 Jul 27;9(8):827

Cheng-Wei Chang, Yuchen Liu, Cheng Jiao, Hongwei Liu, Jie Gong, Xiaochuan Chen, Lung-Ji Chang

19

2022

GD2-specific chimeric antigen receptor-modified T cells for the treatment of refractory and/or recurrent neuroblastoma in pediatric patients

J Cancer Res Clin Oncol. 2022 Oct;148(10):2643-2652

Lihua Yu, Lulu Huang, Danna Lin, Xiaorong Lai, Li Wu, Xu Liao, Jiale Liu, Yinghua Zeng, Lichan Liang, Guanmei Zhang, Bin Wang, Zhu Wu, Shaohua Tao, Yuchen Liu, Cheng Jiao, Lung-Ji Chang, Lihua Yang

20

2022

Molecular therapeutics of hemophilia A and B

Expert Rev Hematol. 2022 May;15(5):431-441

Jie Gong, Hao-Lin Wang, Lung-Ji Chang

21

2022

Intracerebral lentiviral ABCD1 gene therapy in an early disease onset ALD mouse model

Gene Ther. 2023 Feb;30(1-2):18-30

Jie Gong, Yunyun Liu, Tsai-Hua Chung, Liu Xu, Troy C Lund, Lung-Ji Chang

22

2022

Lentiviral gene therapy of chronic granulomatous disease: functional assessment of universal and tissue-specific promoters

Hum Gene Ther. 2023 Jan;34(1-2):19-29

Haokun Yuan, Xiaomei Wu, Hongwei Liu, Lung-Ji Chang

23

2023

Safety and antitumor activity of GD2-Specific 4SCAR-T cells in patients with glioblastoma

Mol Cancer. 2023 Jan 9;22(1):3

Zhuohao Liu, Jiayi Zhou, Xinzhi Yang, Yuchen Liu, Chang Zou, Wen Lv, Cheng Chen, Kenneth King-yip Cheng, Tao Chen, Lung-Ji Chang, Dinglan Wu, and Jie Mao

24

2023

4SCAR2.0 therapy for the
management of post transplantation relapse of B-cell
acute lymphoblastic leukemia

Frontiers in Hematology 09 November 2023 DOI 10.3389/frhem.2023.1251622

Rui Zhang,Juan Xiao,Yuan Sun,Sanfang Tu,Yuhua Li,Leping Zhang,Yifei Cheng,Song Xue,Yongping Zhang,Bin Wang,Huyong Zheng,Nobuhiro Nishio,Yoshiyuki Takahashi,Seiji Kojima,Yingying Wang,Biljana Horn,and Lung-Ji Chang

25

2024

Phase I clinical trial of intracerebral injection of lentiviral-ABCD1 for the

treatment of cerebral adrenoleukodystrophy

Science Bulletin

Volume 69, Issue 16, 30 August 2024, Pages 2596-2603

Qiu-Hong Wang , Jing Wang , Zhi-Pei Ling  , Zhi-Qiang Cui  , Jie Gong , Rui Zhang  , Shi-Jun Li  ,

Yang-Yang Wang , Rui Yang , De-Hui Huang , Wen He  , Jing Gao  , Chen Feng  , Pei-Li Hu  , Li-Ying Liu ,

Lung-Ji Chang  , Li-Ping Zou