Prof. Chang obtained a doctorate (Ph.D.) in Microbiology from the University of Iowa, Iowa City, USA.  Dr. Chang is a tenured Full Professor in University of Florida College of Medicine, and appointed as President of Shenzhen Geno-immune Medical Institute (GIMI), Shenzhen, China. He has published more than 150 scientific articles and filed more than 40 US/International patents. Prof. Chang develops novel molecular biology and gene therapy tools and participates in individualized medical treatments in multiple clinical trials applying gene and cell based therapeutics. He served as Scientific Consultant for United Nations from 2002-2009, and served as Special Government Employee for US Food and Drug Administration (FDA) as advisor for Cellular, Tissue and Gene Therapies advisory committee from 2010-2018. He served as a member of International Committee and Viral Vector Committee of the American Society for Gene and Cell Therapy (ASGCT), and served as Editor-in-Chief of Current Gene Therapy, and an editorial board member in multiple international journals.  Prof. Chang’s research Interests include developing lentiviral vectors as gene transfer tools and using innovative approaches to study the development of stem cells and functional immune cells. His research projects have been funded by multiple national and international funds total more than 30 million US dollars. The emphasis of research has been to translate basic science into clinical treatment for genetic diseases, infectious diseases and cancer. Research activities include characterization of cellular and immune modulatory factors that are essential to the development of protective immunity in patients. Innovative immunotherapy approaches are developed for the treatment of genetic diseases, infections and cancer. The long-term goal is to translate basic scientific discovery into clinical applications.

From September 2007 to March 2014, I studied biological engineering as a bachelor and chemical engineering and technology as a master in Beijing institute of Technology . After that, I joined Prof. Chang’s team and participated in preparation and culture of immune cells, helped establish the latest lentiviral production process and gene delivery technology, including CAR T cell preparation, toxicity efficacy testing and clinical cell therapy applications. In 2016, I was a visiting scholar in the laboratory of Prof. Chang at the University of Florida. My expertise and skill proficiency included the following related topics: cell biology (cell culture, transfection, etc., immunology (Western blot, immunofluorescence, ICCS, etc.), molecular biology (cloning, QPCR, etc.). As R&D Director, I have coauthored multiple scientific papers and have filed several patents. 

From 2008 to 2015, I studied in Marine Science as a bachelor and Marine Biology as a master in Xiamen University. After that, I joined Prof. Chang‘s team in 2017 and skilled with the latest lentiviral production process and gene delivery technology, CAR T cell preparation, toxicity efficacy testing and clinical cell therapy applications, with proficiency in the following skills: histology (embedding sectioning, immunohistochemical staining, etc.), cell biology (cell culture, transfection, etc.), immunology (Western blot, immunofluorescence, ICCS, etc.), and clinical grade immune cell manufacture etc..  I have co-authored several articles and have been an inventor of multiple patents.